Four things to know about using intragastric balloon devices to bridge therapy before laparoscopic sleeve gastrectomy

Obesity is a complex challenge affecting millions around the world. One of the exciting developments in minimally invasive care is intragastric balloon therapy, which helps patients lose weight by placing a balloon in the stomach to promote a sense of fullness and reduce appetite. A recent study compared three intragastric balloon systems in people with very high body mass index (BMI) before undergoing bariatric surgery. This study provides helpful real-world insights into how these devices perform in clinical settings. Below, Dr. Alexander Shapsis of EndoSlim Clinic at Atlantic Gastroenterology in Brooklyn, New York, highlights four key takeaways from this research to fully understand the benefits of using this technology and help lead patients toward healthier lifestyles!

1. Adjustability matters: More weight loss with volume changes

One of the standout findings in the study shows that the adjustable intragastric balloon (specifically the Spatz3) produced noticeably greater weight loss at six months compared with non-adjustable balloons in similar patients. On average, patients with the adjustable system lost about 25 kilograms, while those with fixed balloons lost around 14 to 16 kilograms under identical conditions. Giving doctors the ability to increase balloon volume partway through treatment may improve intragastric balloon weight-loss outcomes.

2. Treating the stomach as a dynamic organ can improve results

Instead of viewing the stomach like a simple space, this study treats it like a living, responsive organ. The volume adjustment strategy reflects this idea. Because the stomach adapts over time, responding to that adaptation rather than using a one-size-fits-all fixed balloon might be more effective for patients with higher BMIs.

3. Zero early removals is a big deal

In this cohort of 148 patients, the study reported no early balloon removals despite significant volume adjustments. That is encouraging because early removal usually signals intolerance, side effects, or complications. No early removals suggest that this therapy was well-tolerated when paired with thoughtful patient care.

4. Short-term results look promising, though long-term data are still evolving

Broader research on intragastric balloons shows they can achieve meaningful weight loss, often around 10-15% of total body weight at the time of balloon removal. What remains a topic of ongoing research is how well patients maintain weight loss beyond the balloon’s removal. Many studies indicate that some weight regain can occur without lifestyle support and follow-up care.

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